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Early Life Stress Interacts with the Diet...
Journal article

Early Life Stress Interacts with the Diet Deficiency of Omega-3 Fatty Acids during the Life Course Increasing the Metabolic Vulnerability in Adult Rats

Abstract

Early stress can cause metabolic disorders in adulthood. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) deficiency has also been linked to the development of metabolic disorders. The aim of this study was to assess whether an early stressful event such as maternal separation interacts with the nutritional availability of n-3 PUFAs during the life course on metabolic aspects. Litters were randomized into: maternal separated (MS) and non-handled …

Authors

Bernardi JR; Ferreira CF; Senter G; Krolow R; de Aguiar BW; Portella AK; Kauer-Sant'Anna M; Kapczinski F; Dalmaz C; Goldani MZ

Journal

PLOS ONE, Vol. 8, No. 4,

Publisher

Public Library of Science (PLoS)

Publication Date

2013

DOI

10.1371/journal.pone.0062031

ISSN

1932-6203