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Immunoelectron microscopic localization of...
Journal article

Immunoelectron microscopic localization of monoclonal IgM antibodies in gammopathy associated with peripheral demyelinative neuropathy

Abstract

A sural nerve biopsy from a patient with benign monoclonal IgM kappa gammopathy and sensory-motor demyelinative neuropathy, revealed marked loss of myelinated fibers and focal axonal degeneration as well as widespread demyelination and remyelination with onion-skin formation. Almost all meylinated fibers displayed characteristic widening of the myelin lamellae as well as excessive thickness and/or exuberant outfoldings of myelin, reminiscent of …

Authors

Lach B; Rippstein P; Atack D; Afar DEH; Gregor A

Journal

Acta Neuropathologica, Vol. 85, No. 3, pp. 298–307

Publisher

Springer Nature

Publication Date

February 1993

DOI

10.1007/bf00227726

ISSN

0001-6322