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Intercellular coupling mediated by potassium...
Journal article

Intercellular coupling mediated by potassium accumulation in peg-and-socket junctions

Abstract

Coupling of smooth muscle cells is important for coordination of gastrointestinal motility. Small structures called peg-and-socket junctions (PSJs) have been found between muscle cells and may play a role in electrical coupling due to extracellular potassium accumulation in the narrow cleft between the muscle cells. A model was developed in which an electrical boundary element model of the cell morphology is used in conjunction with a finite …

Authors

Vigmond EJ; Bardakjian BL; Thuneberg L; Huizinga JD

Journal

IEEE Transactions on Biomedical Engineering, Vol. 47, No. 12, pp. 1576–1583

Publisher

Institute of Electrical and Electronics Engineers (IEEE)

Publication Date

2000

DOI

10.1109/10.887938

ISSN

0018-9294