Conference
Influences of non-selective interactions of nucleic acids on response rates of nucleic acid fiber optic biosensors
Abstract
Abstract The immobilization of oligonucleotides to solid surfaces can provide a platform of chemistry that is suitable for the development of biosensor and microarray technologies. Experiments were performed using a fiber optic nucleic acid biosensor based on total internal reflection fluorescence to examine the effects of the presence of non-complementary DNA on the detection of hybridization of complementary target DNA. The work has focused …
Authors
Watterson JH; Piunno PAE; Wust CC; Raha S; Krull UJ
Volume
369
Pagination
pp. 601-608
Publisher
Springer Nature
Publication Date
April 2001
DOI
10.1007/s002160000683
Conference proceedings
Fresenius Journal of Analytical Chemistry
Issue
7-8
ISSN
0937-0633