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Exaggerated systemic antibody response to mucosal...
Journal article

Exaggerated systemic antibody response to mucosal Helicobacter pylori infection in IgA nephropathy

Abstract

Numerous studies in the literature report aberrant immune responsiveness in immunoglobulin A (IgA) nephropathy. However, all these studies investigate immune responses invoked by an artificially engineered antigen challenge. For the first time in IgA nephropathy, we report the systemic humoral responses generated as part of an active mucosal immune response against a common environmental pathogen, Helicobacter pylori (Hp). We studied 22 …

Authors

Barratt J; Bailey EM; Buck KS; Mailley J; Moayyedi P; Feehally J; Turney JH; Crabtree JE; Allen AC

Journal

American Journal of Kidney Diseases, Vol. 33, No. 6, pp. 1049–1057

Publisher

Elsevier

Publication Date

June 1999

DOI

10.1016/s0272-6386(99)70141-1

ISSN

0272-6386