Journal article
Perioperative bridging anticoagulation during dabigatran or warfarin interruption among patients who had an elective surgery or procedure
Abstract
In patients with atrial fibrillation (AF) who require interruption of dabigatran or warfarin for an elective surgery/procedure, the risks and benefits of perioperative bridging anticoagulation is uncertain.We accessed the database from RE-LY, a randomised trial comparing dabigatran with warfarin for stroke prevention in AF, to assess the potential benefits and risks of bridging. In patients who had a first interruption of dabigatran or warfarin …
Authors
Douketis JD; Healey JS; Brueckmann M; Eikelboom JW; Ezekowitz MD; Fraessdorf M; Noack H; Oldgren J; Reilly P; Spyropoulos AC
Journal
Thrombosis and Haemostasis, Vol. 113, No. 03, pp. 625–632
Publisher
Thieme
Publication Date
May 2015
DOI
10.1160/th14-04-0305
ISSN
0340-6245
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAnticoagulantsAtrial FibrillationBlood Loss, SurgicalDabigatranDrug Administration ScheduleElective Surgical ProceduresFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPerioperative CarePostoperative HemorrhagePropensity ScoreProportional Hazards ModelsRandomized Controlled Trials as TopicRetrospective StudiesRisk AssessmentRisk FactorsStrokeSurgical Procedures, OperativeTime FactorsTreatment OutcomeWarfarin