Intracellular localization of TDAG51 modulates its effect on cell death

Our previously findings indicate that T‐cell death associated gene 51 (TDAG51) contributes to cell death in atherosclerotic lesions. To determine if these cell death effects are mediated by TDAG51 intracellular localization, we performed sequence analysis of the TDAG51 cDNA to identify novel cellular targeting domains. This analysis revealed two putative motifs; a nuclear exiting signal (NES) (70‐vasleppvkl‐80) and nuclear localization signal …