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In situ hybridization and immunocytochemical...
Journal article

In situ hybridization and immunocytochemical localization of SERCA2 encoded Ca2+ pump in rabbit heart and stomach

Abstract

Heart tissue contains large amounts of the protein encoded by the Ca2+ pump gene SERCA2. The SERCA2 RNA can be spliced alternatively to produce mRNA encoding the proteins SERCA2a and SERCA2b which differ in their C-terminal sequences. In this study we report the tissue distribution of SERCA2a and SERCA2b isoforms byin situ hybridization to rabbit heart and stomach. The expression of SERCA2 mRNA was high in myocardial cells, being the highest in …

Authors

Mearow KM; Thilander BG; Khan I; Garfield RE; Grover AK

Journal

Molecular and Cellular Biochemistry, Vol. 121, No. 2, pp. 155–165

Publisher

Springer Nature

Publication Date

April 1993

DOI

10.1007/bf00925975

ISSN

0300-8177