Journal article
Evidence for Lateral Transfer of Genes Encoding Ferredoxins, Nitroreductases, NADH Oxidase, and Alcohol Dehydrogenase 3 from Anaerobic Prokaryotes to Giardia lamblia and Entamoeba histolytica
Abstract
Giardia lamblia and Entamoeba histolytica are amitochondriate, microaerophilic protists which use fermentation enzymes like those of bacteria to survive anaerobic conditions within the intestinal lumen. Genes encoding fermentation enzymes and related electron transport peptides (e.g., ferredoxins) in giardia organisms and amebae are hypothesized to be derived from either an ancient anaerobic eukaryote (amitochondriate fossil hypothesis), a …
Authors
Nixon JEJ; Wang A; Field J; Morrison HG; McArthur AG; Sogin ML; Loftus BJ; Samuelson J
Journal
mSphere, Vol. 1, No. 2, pp. 181–190
Publisher
American Society for Microbiology
Publication Date
4 2002
DOI
10.1128/ec.1.2.181-190.2002
ISSN
1556-6811
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Alcohol DehydrogenaseAmino Acid SequenceAnaerobiosisAnimalsBacteriaEntamoeba histolyticaFermentationFerredoxinsGene Transfer, HorizontalGiardia lambliaIron-Sulfur ProteinsMitochondriaModels, BiologicalMolecular Sequence DataMultienzyme ComplexesNADH, NADPH OxidoreductasesNitroreductasesOxidoreductasesPhylogenyProkaryotic CellsSequence AlignmentSequence Analysis, Protein