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Phylogenetic Analysis of the Cytochrome P450 3...
Journal article

Phylogenetic Analysis of the Cytochrome P450 3 (CYP3) Gene Family

Abstract

Cytochrome P450 genes (CYP) constitute a superfamily with members known from the Bacteria, Archaea, and Eukarya. The CYP3 gene family includes the CYP3A and CYP3B subfamilies. Members of the CYP3A subfamily represent the dominant CYP forms expressed in the digestive and respiratory tracts of vertebrates. The CYP3A enzymes metabolize a wide variety of chemically diverse lipophilic organic compounds. To understand vertebrate CYP3 diversity …

Authors

McArthur AG; Hegelund T; Cox RL; Stegeman JJ; Liljenberg M; Olsson U; Sundberg P; Celander MC

Journal

Journal of Molecular Evolution, Vol. 57, No. 2, pp. 200–211

Publisher

Springer Nature

Publication Date

August 2003

DOI

10.1007/s00239-003-2466-x

ISSN

0022-2844