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Evaluation of Stochastic Differential Equation...
Journal article

Evaluation of Stochastic Differential Equation Approximation of Ion Channel Gating Models

Abstract

Fox and Lu derived an algorithm based on stochastic differential equations for approximating the kinetics of ion channel gating that is simpler and faster than “exact” algorithms for simulating Markov process models of channel gating. However, the approximation may not be sufficiently accurate to predict statistics of action potential generation in some cases. The objective of this study was to develop a framework for analyzing the inaccuracies …

Authors

Bruce IC

Journal

Annals of Biomedical Engineering, Vol. 37, No. 4, pp. 824–838

Publisher

Springer Nature

Publication Date

April 2009

DOI

10.1007/s10439-009-9635-z

ISSN

0090-6964