Journal article
Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men
Abstract
We investigated the effect of resistance exercise and feeding on the activation of signaling proteins involved in translation initiation. Nine young men (23.7+/-0.41 yr; BMI=25.5+/-1.0 kg/m2; means+/-SE) were tested twice after they performed a strenuous bout of unilateral resistance exercise, such that their contralateral leg acted as a nonexercised comparator, in either the fasted and fed [1,000 kJ, each 90 min (3 doses): 10 g protein, 41 g …
Authors
Glover EI; Oates BR; Tang JE; Moore DR; Tarnopolsky MA; Phillips SM
Journal
AJP Regulatory Integrative and Comparative Physiology, Vol. 295, No. 2, pp. r604–r610
Publisher
American Physiological Society
Publication Date
8 2008
DOI
10.1152/ajpregu.00097.2008
ISSN
0363-6119
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAmino AcidsBlood GlucoseEatingEukaryotic Initiation Factor-2BExerciseFastingFocal Adhesion Protein-Tyrosine KinasesGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaHumansInsulinMaleMuscle ContractionMuscle ProteinsMuscle, SkeletalPhosphorylationPostprandial PeriodProtein BiosynthesisProtein KinasesProto-Oncogene Proteins c-aktRibosomal Protein S6Ribosomal Protein S6 Kinases, 70-kDaSignal TransductionTOR Serine-Threonine KinasesTime FactorsWeight Lifting