Journal article
Two Weeks of Reduced Activity Decreases Leg Lean Mass and Induces “Anabolic Resistance” of Myofibrillar Protein Synthesis in Healthy Elderly
Abstract
BACKGROUND: Alterations in muscle protein metabolism underlie age-related muscle atrophy. During periods of muscle disuse, muscle protein synthesis is blunted, and muscle atrophy occurs in young and old. The impact of a short reduction in physical activity on muscle protein metabolism in older adults is unknown.
PURPOSE: The aim of this study was to investigate the impact of 14 days of reduced daily steps on fasted and fed-state rates of …
Authors
Breen L; Stokes KA; Churchward-Venne TA; Moore DR; Baker SK; Smith K; Atherton PJ; Phillips SM
Journal
The Journal of Clinical Endocrinology & Metabolism, Vol. 98, No. 6, pp. 2604–2612
Publisher
The Endocrine Society
Publication Date
June 1, 2013
DOI
10.1210/jc.2013-1502
ISSN
0021-972X