Journal article
Changes in expression of the CD200 tolerance‐signaling molecule and its receptor (CD200R) by villus trophoblasts during first trimester missed abortion and in chronic histiocytic intervillositis
Abstract
PROBLEM: Expression of CD200 at the feto-maternal interface is associated with successful murine and human pregnancy. CD200 binding to CD200 receptors on lymphomyeloid cells suppresses inflammation and induces Tregs. CD200 receptors are also expressed on mouse and human placental trophoblast cells. What is the expression of CD200 and CD200R in human missed abortions which have preserved Treg levels and in chronic histiocytic intervillositis …
Authors
Clark DA; Dmetrichuk JM; McCready E; Dhesy‐Thind S; Arredondo JL
Journal
American Journal Of Reproductive Immunology, Vol. 78, No. 1,
Publisher
Wiley
Publication Date
7 2017
DOI
10.1111/aji.12665
ISSN
1046-7408