Journal article
Roflumilast for asthma: Efficacy findings in mechanism of action studies
Abstract
BACKGROUND: The efficacy profile of roflumilast, a phosphodiesterase-4 inhibitor used for the treatment of chronic obstructive pulmonary disease (COPD), is well known. In asthma treatment, much less is understood about the role of roflumilast, particularly its mechanism of action and potential bronchodilatory effects.
AIM: To evaluate the therapeutic efficacy and mechanism of action of roflumilast in patients with asthma using data from eight …
Authors
Bardin P; Kanniess F; Gauvreau G; Bredenbröker D; Rabe KF
Journal
Pulmonary Pharmacology & Therapeutics, Vol. 35, , pp. s4–s10
Publisher
Elsevier
Publication Date
December 2015
DOI
10.1016/j.pupt.2015.08.006
ISSN
1094-5539