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Enhanced infectivity of herpes simplex virus type...
Journal article

Enhanced infectivity of herpes simplex virus type 1 viral DNA in a cell line expressing the trans-inducing factor Vmw65

Abstract

Vmw65 is a structural component of herpes simplex virus (HSV) which is involved in transactivating the expression of the viral immediate-early (IE) genes. To gain further insight into the function of this protein, a cell line, BSV65, was established which expresses biologically active Vmw65 under control of the Moloney leukemia virus long terminal repeat. This cell line was shown to specifically activate IE genes as demonstrated by transient …

Authors

Werstuck G; Bilan P; Capone JP

Journal

Journal of Virology, Vol. 64, No. 3, pp. 984–991

Publisher

American Society for Microbiology

Publication Date

March 1990

DOI

10.1128/jvi.64.3.984-991.1990

ISSN

0022-538X