Journal article
Functional impact of global rare copy number variation in autism spectrum disorders
Abstract
The genetics of autismThe autism spectrum disorders (ASDs) are a group of conditions typically characterized by repetitive behaviour, severely restricted interests and difficulties with social interactions and communication. ASDs are highly heritable, yet the underlying genetic determinants remain largely unknown. A genome-wide analysis reveals that people with ASDs carry a higher load of rare copy-number variants — segments of DNA for which …
Authors
Pinto D; Pagnamenta AT; Klei L; Anney R; Merico D; Regan R; Conroy J; Magalhaes TR; Correia C; Abrahams BS
Journal
Nature, Vol. 466, No. 7304, pp. 368–372
Publisher
Springer Nature
Publication Date
July 2010
DOI
10.1038/nature09146
ISSN
0028-0836