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The Canadian Experience with Intensive...
Journal article

The Canadian Experience with Intensive Fluorouracil, Epirubicin and Cyclophosphamide in Patients with Early Stage Breast Cancer

Abstract

A multicentre dose-finding pilot study was conducted to determine an intensive regimen of fluorouracil (F), epirubicin (E) plus cyclophosphamide (C) [FEC] that was tolerable and acceptable to patients with node-positive operable (n = 266) or locally advanced (n = 22) breast cancer. Consecutive patients were treated with fluorouracil and epirubicin administered intravenously on days 1 and 8, in addition to cyclophosphamide orally for 14 days. …

Authors

Levine MN; Bramwell V; Pritchard K; Perrault D; Findlay B; Abu-Zahra H; Warr D; Arnold A; Shillings J

Journal

Drugs, Vol. 45, No. Suppl 2, pp. 51–59

Publisher

Springer Nature

Publication Date

May 1993

DOI

10.2165/00003495-199300452-00009

ISSN

0012-6667