Journal article
Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion.
Abstract
The effects of (+)-sparteine, a ganglionic blocking agent, on acetylcholine (ACh)-induced membrane currents and on fast excitatory postsynaptic currents (EPSCs) were studied in the neurons of rat isolated superior cervical ganglion, with the whole-cell patch-clamp recording method and the two-electrode voltage-clamp method, respectively. (+)-Sparteine (2 microM) reduced the ACh-induced current caused by activation of nicotinic ACh receptors …
Authors
Voitenko S; Purnyn S; Omeltchenko I; Dyadyusha GG; Zhorov B; Brovtsina N; Skok V
Journal
Molecular Pharmacology, Vol. 40, No. 2, pp. 180–185
Publisher
Elsevier
Publication Date
August 1991
DOI
10.1016/s0026-895x(25)12930-1
ISSN
0026-895X