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A Comparison of Low-Molecular-Weight Heparin with...
Journal article

A Comparison of Low-Molecular-Weight Heparin with Unfractionated Heparin for Unstable Coronary Artery Disease

Abstract

BACKGROUND: Antithrombotic therapy with heparin plus aspirin reduces the rate of ischemic events in patients with unstable coronary artery disease. Low-molecular-weight heparin has a more predictable anticoagulant effect than standard unfractionated heparin, is easier to administer, and does not require monitoring. METHODS: In a double-blind, placebo-controlled study, we randomly assigned 3171 patients with angina at rest or non-Q-wave …

Authors

Cohen M; Demers C; Gurfinkel EP; Turpie AGG; Fromell GJ; Goodman S; Langer A; Califf RM; Fox KAA; Premmereur J

Journal

New England Journal of Medicine, Vol. 337, No. 7, pp. 447–452

Publisher

Massachusetts Medical Society

Publication Date

August 14, 1997

DOI

10.1056/nejm199708143370702

ISSN

0028-4793