Journal article
Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis.
Abstract
BACKGROUND: Antibiotic treatment may disturb the resistance of gastrointestinal flora to colonization. This may result in complications, the most serious of which is Clostridium difficile–associated diarrhea (CDAD).
PURPOSE: To assess the efficacy and safety of probiotics for the prevention of CDAD in adults and children receiving antibiotics.
Authors
Johnston BC; Ma SSY; Goldenberg JZ; Thorlund K; Vandvik PO; Loeb M; Guyatt GH
Journal
Annals of Internal Medicine, Vol. 157, No. 12, pp. 878–888
Publisher
American College of Physicians
Publication Date
December 18, 2012
DOI
10.7326/0003-4819-157-12-201212180-00563
ISSN
1056-8751