Journal article
Magnetically Triggered Nanocomposite Membranes: A Versatile Platform for Triggered Drug Release
Abstract
Drug delivery devices based on nanocomposite membranes containing thermoresponsive nanogels and superparamagnetic nanoparticles have been demonstrated to provide reversible, on-off drug release upon application (and removal) of an oscillating magnetic field. We show that the dose of drug delivered across the membrane can be tuned by engineering the phase transition temperature of the nanogel, the loading density of nanogels in the membrane, and …
Authors
Hoare T; Timko BP; Santamaria J; Goya GF; Irusta S; Lau S; Stefanescu CF; Lin D; Langer R; Kohane DS
Journal
Nano Letters, Vol. 11, No. 3, pp. 1395–1400
Publisher
American Chemical Society (ACS)
Publication Date
March 9, 2011
DOI
10.1021/nl200494t
ISSN
1530-6984