Journal article
Oxidative stress in prostate cancer: changing research concepts towards a novel paradigm for prevention and therapeutics
Abstract
A mounting body of evidence suggests that increased production of reactive oxygen species (ROS) is linked to aging processes and to the etiopathogenesis of aging-related diseases, such as cancer, diabetes, atherosclerosis and degenerative diseases like Parkinson’s and Alzheimer’s. Excess ROS are deleterious to normal cells, while in cancer cells, they can lead to accelerated tumorigenesis. In prostate cancer (PC), oxidative stress, an innate …
Authors
Paschos A; Pandya R; Duivenvoorden WCM; Pinthus JH
Journal
Prostate Cancer and Prostatic Diseases, Vol. 16, No. 3, pp. 217–225
Publisher
Springer Nature
Publication Date
9 2013
DOI
10.1038/pcan.2013.13
ISSN
1365-7852