Journal article
Effect of a simple two‐step warfarin dosing algorithm on anticoagulant control as measured by time in therapeutic range: a pilot study
Abstract
BACKGROUND: The efficacy and safety of vitamin K antagonists for the prevention of thromboembolism are dependent on the time for which the International Normalized Ratio (INR) is in the therapeutic range. The objective of our study was to determine the effect of introducing a simple two-step dosing algorithm, as compared with dosing by anticoagulation clinic staffs on the basis of their experience, on time in therapeutic range (TTR) of warfarin …
Authors
KIM Y; NIEUWLAAT R; CONNOLLY SJ; SCHULMAN S; MEIJER K; RAJU N; KAATZ S; EIKELBOOM JW
Journal
Journal of Thrombosis and Haemostasis, Vol. 8, No. 1, pp. 101–106
Publisher
Elsevier
Publication Date
January 2010
DOI
10.1111/j.1538-7836.2009.03652.x
ISSN
1538-7933
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Administration, OralAgedAlgorithmsAmbulatory Care FacilitiesAnticoagulantsBlood CoagulationChi-Square DistributionDrug Administration ScheduleDrug Dosage CalculationsDrug MonitoringFemaleHumansInternational Normalized RatioLinear ModelsMaleMiddle AgedOntarioPilot ProjectsPredictive Value of TestsProgram EvaluationTime FactorsVitamin KWarfarin