Journal article
Small airway epithelial-C/EBPβ is increased in patients with advanced COPD
Abstract
The expression of CCAAT/enhancer-binding protein (C/EBP)β in the small airway epithelium of COPD is unknown. C/EBPβ was assessed in peripheral lung tissue of non-smoking/smoking controls and patients with GOLD I-IV COPD by quantitative immunohistochemistry. The expression of C/EBPβ was decreased in smokers compared to never smokers. Furthermore, C/EBPβ was significantly elevated in advanced COPD vs. asymptomatic smokers, and the expression …
Authors
Mori M; Bjermer L; Erjefält JS; Stampfli MR; Roos AB
Journal
Respiratory Research, Vol. 16, No. 1,
Publisher
Springer Nature
Publication Date
December 2015
DOI
10.1186/s12931-015-0297-0
ISSN
1465-9921