Conference
Effects of Multimerin 1 on Platelet and Plasma FV as Determined by Calibrated Automated Thrombography.
Abstract
Abstract
Multimerin 1 (MMRN1) is a protein that is not found in plasma and that is complexed with factor V (FV) in platelet α-granules. Following thrombin activation, platelet FV and MMRN1 are released, and FV is converted to Va, promoting its dissociation from MMRN1. Recent studies identifying functional overlap between FV/Va binding sites for phospholipids and MMRN1, and unanswered questions about the functional consequences …
Authors
Tasneem S; Jeimy SB; Fuller N; McKay H; Nicolaes GAF; Hayward CPM
Volume
108
Publisher
American Society of Hematology
Publication Date
November 16, 2006
DOI
10.1182/blood.v108.11.1607.1607
Conference proceedings
Blood
Issue
11
ISSN
0006-4971