Journal article
Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomised controlled trial
Abstract
BACKGROUND: Warfarin-associated coagulopathy is a frequent clinical complication. We aimed to assess whether treatment with vitamin K is safe and more effective than placebo in rapidly lowering the international normalised ratio (INR) into the therapeutic range in over anticoagulated patients receiving warfarin.
METHODS: We did a multicentre, double-blind, placebo-controlled, randomised trial in five tertiary care hospitals. In this study, …
Authors
Crowther MA; Julian J; McCarty D; Douketis J; Kovacs M; Biagoni L; Schnurr T; McGinnis J; Gent M; Hirsh J
Journal
The Lancet, Vol. 356, No. 9241, pp. 1551–1553
Publisher
Elsevier
Publication Date
November 2000
DOI
10.1016/s0140-6736(00)03125-1
ISSN
0140-6736