Journal article
FcγRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia
Abstract
BACKGROUND: A significant challenge in the management of heparin-induced thrombocytopenia (HIT) patients is making a timely and accurate diagnosis. The readily available enzyme immunoassays (EIAs) have low specificities. In contrast, platelet activation assays have higher specificities, but they are technically demanding and not widely available. In addition, ~ 10% of samples referred for HIT testing are initially classified as indeterminate by …
Authors
Nazi I; Arnold DM; Smith JW; Horsewood P; Moore JC; Warkentin TE; Crowther MA; Kelton JG
Journal
Journal of Thrombosis and Haemostasis, Vol. 11, No. 6, pp. 1146–1153
Publisher
Elsevier
Publication Date
June 2013
DOI
10.1111/jth.12208
ISSN
1538-7933