Journal article
Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model
Abstract
The objective of this study was to assess the effects of flaxseed and flax oil diets in the rat renal ablation model. Flaxseed is a rich source of alpha-linolenic acid, an 18:3n3 omega-3 fatty acid, which has anti-atherogenic and anti-inflammatory properties. Flaxseed, but not flax oil, is also rich in lignans, which are platelet-activating factor-receptor antagonists. Rats were subjected to 5/6 nephrectomy, fed a regular laboratory diet (RLD) …
Authors
Ingram AJ; Parbtani A; Clark WF; Spanner E; Huff MW; Philbrick DJ; Holub BJ
Journal
American Journal of Kidney Diseases, Vol. 25, No. 2, pp. 320–329
Publisher
Elsevier
Publication Date
February 1995
DOI
10.1016/0272-6386(95)90015-2
ISSN
0272-6386
Fields of Research (FoR)
Medical Subject Headings (MeSH)
6-Ketoprostaglandin F1 alphaAnalysis of VarianceAnimalsBlood PressureDisease Models, AnimalEicosapentaenoic AcidFatty Acids, Omega-3Glomerular Filtration RateGlomerulosclerosis, Focal SegmentalKidneyKidney Failure, ChronicLigationLinseed OilLipidsMaleNephrectomyPlants, EdibleProteinuriaRatsRats, Sprague-DawleyRenal ArterySeedsThromboxane B2alpha-Linolenic Acid