Journal article
Systematic Review and Meta-Analysis: Infliximab or Cyclosporine as Rescue Therapy in Patients With Severe Ulcerative Colitis Refractory to Steroids
Abstract
OBJECTIVES: Acute severe steroid-refractory ulcerative colitis (UC) carries a poor prognosis and requires optimal management. A systematic review and meta-analysis were conducted to assess cyclosporine and infliximab (IFX) as rescue agents in patients with steroid-refractory UC.
METHODS: A literature search identified studies that investigated IFX and cyclosporine in steroid-refractory UC patients. The primary outcome was short-term response to …
Authors
Narula N; Marshall JK; Colombel J-F; Leontiadis GI; Williams JG; Muqtadir Z; Reinisch W
Journal
The American Journal of Gastroenterology, Vol. 111, No. 4,
Publisher
Wolters Kluwer
Publication Date
April 2016
DOI
10.1038/ajg.2016.7
ISSN
0002-9270