Journal article
Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics
Abstract
BACKGROUND: Interleukin (IL)-25 plays a pivotal role in type 2 immune responses. In a baseline cross-sectional study, we previously showed that IL-25 plasma levels and IL-25 receptor (IL-25R: IL-17RA, IL-17RB, and IL-17RA/RB) expression on mature blood eosinophils are increased in atopic asthmatics compared to normal nonatopic controls. This study investigated allergen-induced changes in IL-25 and IL-25R expression in eosinophils from …
Authors
Tang W; Smith SG; Salter B; Oliveria JP; Mitchell P; Nusca GM; Howie K; Gauvreau GM; O'Byrne PM; Sehmi R
Journal
International Archives of Allergy and Immunology, Vol. 170, No. 4, pp. 234–242
Publisher
Karger Publishers
Publication Date
2016
DOI
10.1159/000449248
ISSN
1018-2438