Journal article
Influence of the Tissue Microenvironment on Toll-Like Receptor Expression by CD11c+ Antigen-Presenting Cells Isolated from Mucosal Tissues▿
Abstract
It is recognized that functional activities of antigen-presenting cells (APCs) in mucosal tissue sites differ from those of systemic APCs; however, it is unknown whether there are further differences between APC populations residing in different mucosal sites. In this study, we directly compared murine CD11c+ APCs isolated from colon, lung, and spleen and found that APCs isolated from these tissues differ considerably in Toll-like receptor …
Authors
Takenaka S; McCormick S; Safroneeva E; Xing Z; Gauldie J
Journal
mSphere, Vol. 16, No. 11, pp. 1615–1623
Publisher
American Society for Microbiology
Publication Date
November 2009
DOI
10.1128/cvi.00216-09
ISSN
1556-6811