Journal article
Effect of Intravenous Iron Sucrose on Exercise Tolerance in Anemic and Nonanemic Patients With Symptomatic Chronic Heart Failure and Iron Deficiency FERRIC-HF: A Randomized, Controlled, Observer-Blinded Trial
Abstract
OBJECTIVES: We tested the hypothesis that intravenous iron improves exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure (CHF) and iron deficiency.
BACKGROUND: Anemia is common in heart failure. Iron metabolism is disturbed, and administration of iron might improve both symptoms and exercise tolerance.
Authors
Okonko DO; Grzeslo A; Witkowski T; Mandal AKJ; Slater RM; Roughton M; Foldes G; Thum T; Majda J; Banasiak W
Journal
Journal of the American College of Cardiology, Vol. 51, No. 2, pp. 103–112
Publisher
Elsevier
Publication Date
January 2008
DOI
10.1016/j.jacc.2007.09.036
ISSN
0735-1097
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedAnalysis of VarianceAnemia, Iron-DeficiencyChronic DiseaseConfidence IntervalsDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleExercise ToleranceFemaleFerric CompoundsFollow-Up StudiesHeart FailureHumansInfusions, IntravenousMaleMiddle AgedOxygen ConsumptionProbabilityProspective StudiesReference ValuesRisk AssessmentSurvival RateTreatment Outcome