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Fetal and Neonatal Exposure to Nicotine Disrupts...
Journal article

Fetal and Neonatal Exposure to Nicotine Disrupts Postnatal Lung Development in Rats: Role of VEGF and Its Receptors

Abstract

Many women are unable to quit smoking during pregnancy and therefore are prescribed drugs, including nicotine (nicotine replacement therapy [NRT]), to aid with smoking cessation. However, the consequences to the offspring of pregnant NRT users have not been well studied. The goals of this study were to determine the consequences of fetal and neonatal exposure to nicotine on lung development and function. Female rats were exposed to nicotine for …

Authors

Petre MA; Petrik J; Ellis R; Inman MD; Holloway AC; Labiris NR

Journal

International Journal of Toxicology, Vol. 30, No. 2, pp. 244–252

Publisher

SAGE Publications

Publication Date

March 2011

DOI

10.1177/1091581810395332

ISSN

1091-5818