Journal article
Oral Treatment with Live Lactobacillus reuteri Inhibits the Allergic Airway Response in Mice
Abstract
RATIONALE: Clinical trials have demonstrated that probiotics may be effective in the treatment and prevention of atopic disease in children but there have been few reports of therapeutic effects of oral probiotics outside the gastrointestinal tract.
OBJECTIVES: We investigated the effect of two probiotic organisms on the response to antigen challenge in a mouse model of allergic airway inflammation.
Authors
Forsythe P; Inman MD; Bienenstock J
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 175, No. 6, pp. 561–569
Publisher
American Thoracic Society
Publication Date
March 15, 2007
DOI
10.1164/rccm.200606-821oc
ISSN
1073-449X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Administration, OralAnimalsAsthmaBronchial HyperreactivityBronchoalveolar Lavage FluidBronchoconstrictor AgentsCytokinesDNA, BacterialDisease Models, AnimalEosinophilsIndoleamine-Pyrrole 2,3,-DioxygenaseKynurenineLimosilactobacillus reuteriMaleMethacholine ChlorideMiceMice, Inbred BALB CProbioticsToll-Like Receptor 9Tryptophan