Journal article
The use of alteplase to restore patency of central venous lines in pediatric patients: A cohort study
Abstract
We evaluated the efficacy and safety of alteplase to restore central venous line (CVL) patency in a consecutive cohort study. A uniform, weight-dependent protocol for alteplase administration was established prospectively. For children < or =10 kg, a dose of 0.5 mg was used; for children >10 kg, doses of 1 to 2 mg were used. The alteplase remained instilled for 1 to 4 hours or overnight. Retrospective data accrual found that 25 children received alteplase for a total of 34 courses; 29 (85%) of the …
Authors
Choi M; Massicotte MP; Marzinotto V; Chan AKC; Holmes JL; Andrew M
Journal
The Journal of Pediatrics, Vol. 139, No. 1, pp. 152–156
Publisher
Elsevier
Publication Date
July 2001
DOI
10.1067/mpd.2001.115019
ISSN
0022-3476