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Emptying and refilling of Ca2+ store in tracheal...
Journal article

Emptying and refilling of Ca2+ store in tracheal myocytes as indicated by ACh-evoked currents and contraction

Abstract

Membrane currents and contractions evoked by acetylcholine (ACh) in freshly dissociated canine tracheal myocytes were investigated using the nystatin perforated-patch recording technique. In cells held at -60 mV in the presence of nifedipine, ACh evoked inward current (IACh) and contraction. Caffeine mimicked the effects of ACh. IACh and contractions could be evoked 3-4 min after removing external Ca2+ but were abolished by prolonged exposure …

Authors

Janssen LJ; Sims SM

Journal

American Journal of Physiology, Vol. 265, No. 4, pp. c877–c886

Publisher

American Physiological Society

Publication Date

October 1, 1993

DOI

10.1152/ajpcell.1993.265.4.c877

ISSN

0002-9513