Quantum Dot Biosensors for Ultrasensitive Multiplexed Diagnostics

Colorful bioassays: Time‐ and color‐resolved detection of Förster resonance energy transfer (FRET) from luminescent terbium complexes to different semiconductor quantum dots results in a fivefold multiplexed bioassay with sub‐picomolar detection limits for all five bioanalytes (see picture). The detection of up to five biomarkers occurs with a sensitivity that is 40–‐240‐fold higher than one of the best‐established single‐analyte reference assays.