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Safety, Utility, and Outcomes of Procainamide...
Journal article

Safety, Utility, and Outcomes of Procainamide Challenge for the Diagnosis and Exclusion of Brugada Syndrome.

Abstract

BACKGROUND: The safety, yield, and prognosis of a type 1 procainamide-induced Brugada pattern are incompletely understood and may differ from those of other sodium channel blockers with greater potencies. METHODS: The safety of procainamide infusion and yield of a type 1 Brugada pattern were assessed according to indication in consecutive patients from the Canadian Hearts in Rhythm Organization registry. Outcomes were evaluated in patients with …

Authors

Moore BM; Chan D; Davies B; Laksman ZWM; Roberts JD; Sanatani S; Steinberg C; Tadros R; Cadrin-Tourigny J; MacIntyre C

Journal

Circulation, , ,

Publisher

Wolters Kluwer

Publication Date

December 4, 2025

DOI

10.1161/circulationaha.125.076011

ISSN

0009-7322