Journal article
Epigenetic age predicts depressive symptoms during the COVID-19 pandemic in the Canadian Longitudinal Study on Aging: importance of biological sex.
Abstract
Epigenetic age is a biological metric of overall health and may predict mental health responses to unprecedented stressors. We sought to determine whether epigenetic age acceleration can predict older adults' trajectory of depressive symptoms before and during the COVID-19 pandemic, and whether sex differences exist. Data from baseline (2012-2015), first follow-up (2015-2018), and COVID-19 Baseline survey (April-May 2020) and COVID-19 Exit …
Authors
Barha CK; Liu-Ambrose T; Inkster AM; Falck RS; Burma JS; Kirkland S; Griffith LE; Thompson M; Basta NE; McMillan JM
Journal
Aging, Vol. 17, ,
Publisher
Impact Journals
Publication Date
November 18, 2025
DOI
10.18632/aging.206337
ISSN
0002-0966