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Maternal Diet‐Induced Excess Adiposity in Mice...
Journal article

Maternal Diet‐Induced Excess Adiposity in Mice Disrupts Mid‐Gestation Decidual Immune and Vascular Homeostasis Without Impairing Spiral Artery Remodeling

Abstract

AIM: Maternal excess adiposity (i.e., overweight/obesity) is linked to impaired uteroplacental perfusion, compromised placental development, and increased risk of adverse pregnancy outcomes. Inflammation and immune dysregulation accompanying excess adiposity may disrupt leukocyte-mediated tissue remodeling and immunoregulation, contributing to placental dysfunction. However, the impacts of excess adiposity on populations of innate lymphoid …

Authors

Bellissimo CJ; Yeo E; Ribeiro TA; Jazwiec PA; Ellewela C; Bains J; Lewis AE; Kennedy KM; Ashkar AA; Beristain AG

Journal

Acta Physiologica, Vol. 241, No. 12,

Publisher

Wiley

Publication Date

12 2025

DOI

10.1111/apha.70130

ISSN

1748-1708