Journal article
Neuropeptides accentuate interleukin‐4 induced human immunoglobuline E synthesis in vitro
Abstract
Corticotropin releasing factor, adrenocorticotropic hormone (ACTH) and alpha-melanocyte stimulating hormone either inhibit or enhance in a dose-dependent fashion an interleukin-4 (IL-4) driven human IgE synthesis in vitro. Here, we show that culture conditions strongly influence the earlier observed dose- and donor-dependent effects of adrenocorticotropic hormone. The effect of ACTH on IgE synthesis became only apparent late during culture …
Authors
Aebischer I; Stämpfli MR; Miescher S; Horn M; Zürcher AW; Stadler BM
Journal
Experimental Dermatology, Vol. 5, No. 1, pp. 38–44
Publisher
Wiley
Publication Date
February 1996
DOI
10.1111/j.1600-0625.1996.tb00091.x
ISSN
0906-6705