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Reldesemtiv in Amyotrophic Lateral Sclerosis
Journal article

Reldesemtiv in Amyotrophic Lateral Sclerosis

Abstract

Importance: Treatment options for amyotrophic lateral sclerosis (ALS) remain suboptimal. Results from a phase 2 study of reldesemtiv in ALS suggested that it may slow disease progression. Objective: To assess the effect of reldesemtiv vs placebo on functional outcomes in ALS.

Authors

Shefner JM; Cudkowicz ME; Genge A; Hardiman O; Al-Chalabi A; Andrews JA; Chio A; Corcia P; Couratier P; de Carvalho M

Journal

JAMA Neurology, Vol. 82, No. 5, pp. 477–485

Publisher

American Medical Association (AMA)

Publication Date

May 1, 2025

DOI

10.1001/jamaneurol.2025.0241

ISSN

2168-6149