Journal article
Aerosol Delivery in Ventilated Newborn Pigs: An MRI Evaluation
Abstract
Pulmonary deposition of inhaled drugs in ventilated neonates has not been studied in vivo. The objective of this study was to evaluate pulmonary delivery of gadopentetate dimeglumine (Gd-DTPA) following nebulization in ventilated piglets using magnetic resonance imaging. Seven ventilated piglets (5 ± 2 d old, weight 1.8 ± 0.5 kg) were scanned in the Bruker/Siemens 4T magnetic resonance scanner using T1 weighted spin-echo sequence. Aerosols of …
Authors
Sood BG; Shen Y; Latif Z; Chen X; Sharp J; Neelavalli J; Joshi A; Slovis TL; Haacke EM
Journal
Pediatric Research, Vol. 64, No. 2, pp. 159–164
Publisher
Springer Nature
Publication Date
August 2008
DOI
10.1203/pdr.0b013e3181761841
ISSN
0031-3998