Journal article
Influence of lung extracellular matrix from non-IPF and IPF donors on primary human lung fibroblast biology
Abstract
Fibrosis, a pathological hallmark of various chronic diseases, involves the excessive accumulation of extracellular matrix (ECM) components leading to tissue scarring and functional impairment. Understanding how cells interact with the ECM in fibrotic diseases such as idiopathic pulmonary fibrosis (IPF), is crucial for developing effective therapeutic strategies. This study explores the effects of decellularized extracellular matrix (dECM) …
Authors
Dabaghi M; Singer R; Noble A; Arizpe Tafoya AV; González-Martínez DA; Gupta T; Formosa-Dague C; Rosas IO; Kolb MR; Shargall Y
Journal
Biomaterials Science, Vol. 13, No. 7, pp. 1721–1741
Publisher
Royal Society of Chemistry (RSC)
Publication Date
March 25, 2025
DOI
10.1039/d4bm00906a
ISSN
2047-4830