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Obesity and Metabolic Disease Impair the Anabolic...
Journal article

Obesity and Metabolic Disease Impair the Anabolic Response to Protein Supplementation and Resistance Exercise: A Retrospective Analysis of a Randomized Clinical Trial with Implications for Aging, Sarcopenic Obesity, and Weight Management

Abstract

BACKGROUND: Anabolic resistance accelerates muscle loss in aging and obesity, thus predisposing to sarcopenic obesity. METHODS: In this retrospective analysis of a randomized clinical trial, we examined baseline predictors of the adaptive response to three months of home-based resistance exercise, daily physical activity, and protein-based, multi-ingredient supplementation (MIS) in a cohort of free-living, older males (n = 32).

Authors

Nilsson MI; Xhuti D; de Maat NM; Hettinga BP; Tarnopolsky MA

Journal

Nutrients, Vol. 16, No. 24,

Publisher

MDPI

DOI

10.3390/nu16244407

ISSN

2072-6643