Journal article
Meta‐Analysis: Evaluating Placebo Rates Across Outcomes in Eosinophilic Oesophagitis Randomised Controlled Trials
Abstract
BACKGROUND: High placebo responses have limited drug development in eosinophilic oesophagitis. The optimal configuration of trial outcomes is uncertain.
AIMS: To inform more efficient future trial designs, to characterise clinical, endoscopic and histologic placebo responses in eosinophilic oesophagitis randomised controlled trials (RCTs).
Authors
Rivas A; Ahmed NS; Yuan Y; Qasim A; O'Gorman DB; Feagan BG; Jairath V; Bredenoord AJ; Dellon ES; Ma C
Journal
Alimentary Pharmacology & Therapeutics, Vol. 61, No. 1, pp. 32–43
Publisher
Wiley
Publication Date
January 2025
DOI
10.1111/apt.18382
ISSN
0269-2813