Journal article
Release of atrial natriuretic peptide precedes shedding of the endothelial glycocalyx equally in patients undergoing on- and off-pump coronary artery bypass surgery
Abstract
The present study investigates why shedding of the endothelial glycocalyx occurs both in patients undergoing on- and off-pump coronary artery bypass surgery. Release of atrial natriuretic peptide (ANP) was of special interest, because ANP initiates shedding ex vivo. Three major constituents of the glycocalyx (syndecan-1, heparan sulfate and hyaluronan) were measured in arterial blood of patients undergoing coronary artery bypass surgery with …
Authors
Bruegger D; Schwartz L; Chappell D; Jacob M; Rehm M; Vogeser M; Christ F; Reichart B; Becker BF
Journal
Basic Research in Cardiology, Vol. 106, No. 6, pp. 1111–1121
Publisher
Springer Nature
Publication Date
November 2011
DOI
10.1007/s00395-011-0203-y
ISSN
0300-8428