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Abstract WMP106: Sex-stratified Transethnic GWAS...
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Abstract WMP106: Sex-stratified Transethnic GWAS Meta-analysis Identifies Novel Candidates For Early Onset Ischemic Stroke

Abstract

Background: Early onset ischemic stroke (IS) affects males and females unequally, but the etiologic background of the sex differences remains inadequately understood. We hypothesize that stratifying GWAS by sex provides an opportunity to 1) identify loci that shed light on mechanisms and pathways relevant to sex specific effects in IS and 2) discover novel IS loci. Methods: We performed a sex-stratified transethnic GWAS meta-analysis in 6,879 …

Authors

Tomppo L; Gaynor B; Putaala J; Strbian D; Kõrv J; Vibo R; de Leeuw F-E; Boncoraglio G; Pare G; Markus H

Volume

54

Pagination

pp. awmp106-awmp106

Publisher

Wolters Kluwer

Publication Date

February 2023

DOI

10.1161/str.54.suppl_1.wmp106

Conference proceedings

Stroke

Issue

Suppl_1

ISSN

0039-2499