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Pomalidomide Use and Kidney Outcomes in Patients...
Journal article

Pomalidomide Use and Kidney Outcomes in Patients With Relapsed/Refractory Multiple Myeloma and Chronic Kidney Disease: A Real-World, Population-Based Cohort Study

Abstract

BACKGROUND: Pomalidomide-based regimens are the cornerstone of treatment for relapsed/refractory MM (RRMM). Despite the high incidence of chronic kidney disease (CKD) in RRMM, individuals with advanced CKD have been excluded from phase II/III RCTs, creating a gap in our understanding of the effects of pomalidomide use in patients with RRMM complicated with advanced CKD. We undertook a cohort to study to understand the efficacy safety of …

Authors

Meraz-Munoz A; Mian H; Kirkwood D; Jeyakumar N; McCurdy A; Tangri N; Saskin R; Leung N; Wald R; Kitchlu A

Journal

Clinical Lymphoma Myeloma & Leukemia, Vol. 24, No. 11, pp. e861–e869

Publisher

Elsevier

Publication Date

November 2024

DOI

10.1016/j.clml.2024.07.007

ISSN

2152-2650